منابع مشابه
Methamphetamine Cured my Cocaine Addiction.
Cocaine dependence is an enduring problem and years of research and drug development has yet to produce an efficacious pharmacotherapy. Recent clinical research suggests that chronic treatment with amphetamine-like medications produces tolerance to cocaine's reinforcing effects and may offer a viable pharmacotherapy. Three methamphetamine-dependent participants that had been in our clinical lab...
متن کاملDeveloping Biomarkers for Methamphetamine Addiction
There are an estimated 11.7 million methamphetamine (MA) abusers in the United States and epidemics of MA addiction are occurring worldwide. In our human laboratory and outpatient clinical trials we use innovative methods to quantify the severity of MA addiction and test biomarkers that may predict response to therapy or risk of relapse. One potential biomarker of addiction is the quantity of a...
متن کاملIs there a role for resveratrol and sirtuins in the treatment of cocaine and methamphetamine addiction?
Cocaine and methamphetamine addiction is a significant public health concern. The abuse and dependence of these drugs have a damaging impact on the life of the drug user, as well as on the user’s family and community. The development of pharmacotherapies against stimulant addiction is critical, as there are no consistentlysuccessful medications for its treatment[1]. Anti-addiction drug therapie...
متن کاملAddiction to Cocaine and Amphetamine
but not DA reuptake, produce neither significant reinforcement in animal models nor euphoria in humans. Laboratory of Molecular and Developmental Neuroscience Moreover, antidepressants do not produce dependence in humans even with very long-term use. In addition, Massachusetts General Hospital Harvard Medical School lesioning of DA terminals within the NAc or full pharmacological blockade of DA...
متن کاملThe Neurobiology of Cocaine Addiction
Cocaine produces its psychoactive and addictive effects primarily by acting on the brain's limbic system, a set of interconnected regions that regulate pleasure and motivation. An initial, short-term effect -- a buildup of the neurochemical dopamine -- gives rise to euphoria and a desire to take the drug again. Researchers are seeking to understand how cocaine's many longer term effects produce...
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ژورنال
عنوان ژورنال: Journal of Addiction Research & Therapy
سال: 2010
ISSN: 2155-6105
DOI: 10.4172/2155-6105.1000103